Use the link below.
http://www.scbos.com/default.htm
As the web site indicates "... is the official state web portal for anyone with a business or starting a business in South Carolina who needs to file permits, licenses, registrations, or taxes with the state. From the convenience of your computer at anytime, 24 hours a day – 7 days a week, you can take care of your important state filings, and pay for multiple filings and/or taxes with one credit, debit, or EFW payment."