Alan, you use fine drywall screws and a screw gun...no pre-drilling. They shoot right in as the tips are designed to be self-drilling. Just the sound is different than when working with wood! Buuuuuuuurappp! Keep in mind that it's best to use a real screw-gun when working with drywall...the mechanism is designed to cam-out when the screw is set at the proper depth and they also hold the fastener securely.