The reason to use mortice-and-tenon joinery is because (1) it is traditional and you prefer to do things traditionally, (2) the design and size of the joint is up to up you, and this will result in the ideal joinery, which will maximise strength, and (3) the joint is more likely to be reversed more easily in spite of the fact that one can use hide glue with either.
Domino are not just quick and easy, but they are also efficient and strong enough given the joinery needs. For example, the kitchen doors that are my current focus will have a life of, say, 20 years - not because they are built any less strongly than furniture built for 200 years, but because fashion will dictate otherwise. To M&T 20+ doors and drawer fronts (Shaker style) would take a lot, lot longer that to Domino. The end result is the same in looks and strength .... actually, it is easier to get a perfect and repeatable result with the Domino, since the joints are simple butt joints. The Domino is geared to power tools use.
I think that the hand tool worker's dislike if the Domino is more likely to come from the thought that it is too easy, and that it is cheating ... that good joinery is a skill, and that skill takes time to learn ... that skill is part of the learning curve, and is a badge of honour. Using a Domino is like jumping the line. Even a beginner can achieve perfect joints. That is unfair!
I do not plan on using a Domino for the furniture I built for the reasons I outlined above. Nevertheless, I want to feel I am beyond the pettiness of "right and wrong" - I do not believe that there is any such thing. Hand tools are not religion, and building furniture uses a great many skills and tools. The best builders design the piece first and then find a way to construct it. One will be limited in scope if you only consider handtools for all tasks (unless all you plan to do is recreacte the past, which is reasonable as well).
Regards from Perth
Derek