bahh.. i was just about to say the same thing that jason said, but he beat me to it.
I wouldn't go thicker than 4" because hold fasts wouldn't work well, and because the wait doesn't offer a practical benefit above that. It is still nice sometimes to be able to move the bench a little. A 650 pound bench doesn't have anything over a properly made 300 pound bench when planing something, nor when chiseling, etc.