Driving on the right in Ireland for ten days was not difficult at all.
I made only one mistake that I know of and it resulted in a courteous little horn toot, not a blaring horn. I love the Irish, so warm and courteous even when I messed up on that four lane road.
In Rome, the driving didn't seem all that difficult. We took only buses and cabs, though. The tough part would have been parking. They park everywhere, even on corners. On the Amalfi Coast I inquired and parking there was 40 Euros an hour. We were in a bus.
In Rome, we mostly walked and took trains.