Bobby, My brother-in -law built a 36 X 80 pole barn for his logging truck. Mind you this is in western upper Michigan where they typically have 3 seasons of good hockey weather and 1 of rough sledding. It's Usual to have 300+ inches of snow per year. He uses an out-door wood fired stove (central boiler) and has radiant heat in the barn including the pit that runs down the middle. I've worked in my t-shirt in that barn when it was -10 to -20 outside. It stays around 75 in there.
I'm thinking about adding to my pole barn to expand the wood shop, and am also thinking about putting radiant heat in the new 12 x 32 section before I pour the floor. I know it is important to put enough insulation down under the slab. I would think the amount would depend on your local average temperatures. More insulation is always better. Incidentally, I'm looking into reject foam insulated panels for the addition walls. I have been told that they go for $1 per sq. ft. @ 4" or 6" thick & they have a high R-value. I figure that if the addition's radiant heat isn't enough to heat the whole shop, I will look around for an old radiator or two to supplement. Heck, maybe I'll turn it into a hill billy shop and just hook up a bunch of old auto radiators and run a fan over them