When I was interested in giving this a shot, I searched all of the forums on information related to installing a window unit as a method for cooling a garage. I got mixed data. Essentially comments like "It depends on the BTU, R-factor, Realtive temperature, etc"
So, I bit the bullet, and installed a 10,000 btu Frigidaire through a hole cut in the wall at 6' height. I have hardiplank on the outside, and 3/4" sheetrock on the inside with fiberglass batting inside the wall. My garage door is insualted with styrofoam sheet inserts. The cieling does not exist a and is open all the way to the rafters. (This is the part that I assumed would give me problems).
After I installed the A/C, I sealed up a few minor areas where cool air could escape and I also re-adjusted my garage door for a tighter fit when closed.
This weekend, outside temperature was 95F and inside my garage, the temperature was hovering around 75F.
Just for kicks, I left the A/C running all night set at 60F and this morning when I went in to check on things, the outside door knob was dripping condensation. It miraculously reached 62F during the night at some point.
So, from experience, I must say that with a window unit at 10,000 BTU, it is possible to get a 20F Degree difference in temperature in a ~400SqFt area with a little insulation in the walls.
If anyone is thinking about adding an A/C to their shop to survive the summer months (especially in the south), I'd reccomend it. My wife has already exclaimed, "No television out there". Yeah, its that comfy. Now I just need to find some nice bar stools, and install a bar, and maybe a used refrigerator and another cable box.... I mean, a new SCMS, Planer, and DC System....