I've been thinking about the same problem. I have roll up overhead doors that don't seal. Heat and cold are part of the problem and during the spring and summer I get mud daubers (wasps) that build their mud nests in every conceivable hole, nook and cranny. My garage doors are also the main ingress and egress for the house. So to keep the shop from getting too dirty (Har!) I try to keep the big doors closed which means opening and closing the garage doors everytime someone wants to go in. This gets old. I'm going to build 4 carriage house doors that can be insulated and sealed to solve all 3 problems. At least, once my shop is done being painted and set up.