I posed this exact question to Ed the original clearvue guy a few years ago. He didn't have a hard answer but did say they had one they used for testing - I think the impellers but could have been the finished cyclones - that got started a dozen or more times an hour (every 5 minutes!) for 8 hours a day and had been happy for over a year.

I got from that conversation that as long as I doing something less than that I would be fine. I sure hope so as mine is buried in the overhead in a muffled closet and would be a world class PITA to swap out.