Well-jointed edges form a really strong butt-joint in under five minutes. Tight-fitting M&T or dovetail joints swell and lock almost instantly with water-based glues. I glue up panels vertically and spread glue with the higher board -- which also creates a nice initial tack. I try hard to unclamp in half an hour, to chisel off the soft "string of pearls" squeeze out. Also found many woods develop startling shadow lines if clamped overnight: my glueups take place near large windows facing morning sun.
Last week, I went from raw beech to 19 glued-up door panels in one long day. Glue up in batches of six or seven, rotate them thru as fast as possible. Nice thing about vertical gluing, it leaves you plenty of shop room to work in.