I'm guessing you don't remember what it was like when you learned to ride a bike, set up a component stereo system, drive a car, fly an airplane, use your first word processor, or any of a myriad number of other tasks that you now take for granted as being intuitive and easy as dirt. What is the precedence for why you should be able to successfully and safely use ANY new machine like a laser engraver with absolutely no training or guidance? That being asked, it doesn't mean it isn't possible, since I had no training or guidance when I started using CorelDraw other than a few 'tube videos to figure out how certain tools worked, and nothing but the user manual to help set up and start using my first Epilog (not even a manual when i got the next gen Epilog), and I still have both eyes, all fingers, and those lasers have earned a nice living for me over the past five years. However, such anecdotal experience doesn't mean it's a reasonable goal.
I have no clue what your problem is here... Please explain how it falls down when you get into the drivers because I can't recall any problem with organization and labels. Now, I'm just getting started with a ULS system and find the machine interface has lots of very useful options but, for now, confusing to me complexity that I don't experience with the Epilog...